The Mouse Anti Human Phenylethanolamine-N-Methyltransferase Antibody from MyBioSource.com is a Mouse Monoclonal antibody to phenylethanolamine N-methyltransferase, and PNMT. This antibody recognizes Human antigen. The Mouse Anti Human Phenylethanolamine-N-Methyltransferase Antibody has been validated for the following applications: ELISA, and Western Blot.
Description
Introduction: PNMT is an enzyme located in the adrenal medulla and it catalyzes the final step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). PNMT has beta-carboline 2N-methyltransferase activity. PNMT takes part in regulating epinephrine production. Glucocorticoid receptors form multimers of PNMT independent of the DNA binding domain. PNMT expression is regulated late in mouse gestation by AP2-alpha and glucocorticoids